RNA Modification and Processing
Willkommen beim Transregio 319 RMaP
Was ist RMaP?
Der Transregio 319 RMaP vereint als Forschungsgemeinschaft die folgenden Schwerpunkte:
Molekularbiologie, Biochemie, Zellbiologie, chemische Biologie, biophysikalische Chemie, Strukturbiologie, Entwicklungsbiologie, Genetik und Bioinformatik.
Projektleiter in RMaP
Fabian Barthels
JGU
Falk Butter
JGU A03, C03
Tamer Butto
JGU
Prof. Dr. Alexander Dalpke
TU-Dresden A03
Prof. Dr. Christoph Dieterich
Uni-HD B01, C02
Prof. Dr. Michaela Frye
UDKFZ A01
Prof. Dr. Mark Helm
JGU A05, C01, C03
Dr. Martin Hengesbach
JGU B06
Prof. Dr. Andreas Hildebrandt
JGU C01, C02
Prof. Dr. Andres Jäschke
Uni-HD A02, C03
Prof. Dr. René Ketting
JGU B04
Dr. Julian König
JGU B01
Prof. Dr. Frank Lyko
DKFZ A01
Prof. Dr. F. Nina Papasvasiliou
DKFZ A04
Dr. Jirka Peschek
Uni-HD A06
Prof. Dr. Jean-Yves Roignant
JGU B01
Dr. Alessia Ruggieri
Uni-HD A05, IRTG
Prof. Dr. Tanja Schirmeister
JGU A01
Bertil Schmidt, Prof. Dr.
JGU C01
Prof. Dr. Irmgard Sinning
Uni-HD B03
Struktur von RMaP
A „Modifications look for Processing“
B „Processing looks for Modifications“
C „New RNA Technology for RMaP“
TRR Sprecherbüro
Prof. Dr. Mark Helm
Sprecher
Dr. Marion Stemke
Koordinator
Claudia Alihodzic
Administration TRR319
Doris Ebeling
Administration & Gleichberechtigung
Doris Gebhardt
Administration & Gleichstellung
Das Scientific Board von RMaP
Aktuelle Publikationen des TRR 319
Sun Y, Piechotta M, Naarmann-de Vries I, Dieterich C, Ehrenhofer-Murray AE. Detection of queuosine and queuosine precursors in tRNAs by direct RNA sequencing. Nucleic Acids Res. 2023 Oct 9:gkad826. doi: 10.1093/nar/gkad826. Epub ahead of print. PMID: 37811872.
Podvalnaya N, Bronkhorst AW, Lichtenberger R, Hellmann S, Nischwitz E, Falk T, Karaulanov E, Butter F, Falk S, Ketting RF. piRNA processing by a trimeric Schlafen-domain nuclease. Nature. 2023 Oct;622(7982):402-409. doi: 10.1038/s41586-023-06588-2. Epub 2023 Sep 27. PMID: 37758951; PMCID: PMC10567574.
Wierczeiko A, Pastore S, Mündnich S, Busch AM, Dietrich V, Helm M, Butto T, Gerber S. NanopoReaTA: a user-friendly tool for nanopore-seq real-time transcriptional analysis. Bioinformatics. 2023 Aug 7:btad492. doi: 10.1093/bioinformatics/btad492. Epub ahead of print. PMID: 37549052.
García-Vílchez R, Añazco-Guenkova AM, Dietmann S, López J, Morón-Calvente V, D’Ambrosi S, Nombela P, Zamacola K, Mendizabal I, García-Longarte S, Zabala-Letona A, Astobiza I, Fernández S, Paniagua A, Miguel-López B, Marchand V, Alonso-López D, Merkel A, García-Tuñón I, Ugalde-Olano A, Loizaga-Iriarte A, Lacasa-Viscasillas I, Unda M, Azkargorta M, Elortza F, Bárcena L, Gonzalez-Lopez M, Aransay AM, Di Domenico T, Sánchez-Martín MA, De Las Rivas J, Guil S, Motorin Y, Helm M, Pandolfi PP, Carracedo A, Blanco S. METTL1 promotes tumorigenesis through tRNA-derived fragment biogenesis in prostate cancer. Mol Cancer. 2023 Jul 29;22(1):119. doi: 10.1186/s12943-023-01809-8. PMID: 37516825; PMCID: PMC10386714.
Koch J, Neuberger M, Schmidt-Dengler M, Xu J, Carneiro VC, Ellinger J, Kriegmair MC, Nuhn P, Erben P, Michel MS, Helm M, Rodríguez-Paredes M, Nientiedt M, Lyko F. Reinvestigating the clinical relevance of the m6A writer METTL3 in urothelial carcinoma of the bladder. iScience. 2023 Jul 11;26(8):107300. doi: 10.1016/j.isci.2023.107300. PMID: 37554463; PMCID: PMC10405067.
Iyer KV, Müller M, Tittel LS, Winz ML. Molecular Highway Patrol for Ribosome Collisions. Chembiochem. 2023 Jun 29:e202300264. doi: 10.1002/cbic.202300264. Epub ahead of print. PMID: 37382189.
Yan L, Yin Z, Zhang H, Zhao Z, Wang M, Müller A, Kallenborn F, Wichmann A, Wei Y, Niu B, Schmidt B, Liu W. RabbitQCPlus 2.0: More Efficient and Versatile Quality Control for Sequencing Data. Methods. 2023 Jun 15:S1046-2023(23)00099-3. doi: 10.1016/j.ymeth.2023.06.007. PMID: 37330158.
Fradera-Sola A, Nischwitz E, Bayer ME, Luck K, Butter F. RNA-dependent interactome allows network-based assignment of RNA-binding protein function. Nucleic Acids Res. 2023 Jun 9;51(10):5162-5176. doi: 10.1093/nar/gkad245. PMID: 37070168; PMCID: PMC10250244.
Zhang H, Song H, Xu X, Chang Q, Wang M, Wei Y, Yin Z, Schmidt B, Liu W. RabbitFX: Efficient Framework for FASTA/Q File Parsing on Modern Multi-Core Platforms. IEEE/ACM Trans Comput Biol Bioinform. 2023 Jun 5;20(3):2341-2348. doi: 10.1109/TCBB.2022.3219114. Epub 2023 Jun 5. PMID: 36327193.
Eine aktuelle Auflistung der TRR-Publikationen finden Sie hier.
