RNA Modification and Processing
Welcome to Transregio 319 RMaP
What is RMaP?
Transregio 319 RMaP is a joint venture combining:
Molecular Biology, Biochemistry, Cellular Biology, Chemical Biology, Biophysical Chemistry, Structural Biology, Developmental Biology, Genetics, Bioinformatics.
Principal Investigators of RMaP
Fabian Barthels
JGU
Falk Butter
JGU A03, C03
Tamer Butto
JGU
Prof. Dr. Alexander Dalpke
TU-Dresden A03
Prof. Dr. Christoph Dieterich
Uni-HD B01, C02
Prof. Dr. Michaela Frye
UDKFZ A01
Prof. Dr. Mark Helm
JGU A05, C01, C03
Dr. Martin Hengesbach
JGU B06
Prof. Dr. Andreas Hildebrandt
JGU C01, C02
Prof. Dr. Andres Jäschke
Uni-HD A02, C03
Prof. Dr. René Ketting
JGU B04
Dr. Julian König
JGU B01
Prof. Dr. Frank Lyko
DKFZ A01
Prof. Dr. F. Nina Papasvasiliou
DKFZ A04
Dr. Jirka Peschek
Uni-HD A06
Prof. Dr. Jean-Yves Roignant
JGU B01
Dr. Alessia Ruggieri
Uni-HD A05, IRTG
Prof. Dr. Tanja Schirmeister
JGU A01
Bertil Schmidt, Prof. Dr.
JGU C01
Prof. Dr. Irmgard Sinning
Uni-HD B03
Prof. Dr. Dr. Georg Stöcklin
Uni-HD A04
Dr. Francesca Tuorto
Uni-HD A06
Dr. Marie-Luise Winz
JGU B05
Structure of RMaP
A „Modificationslook for Processing“
B „Processing looks for Modifications“
C „New RNA Technology for RMaP“
TRR Speaker Office
Prof. Dr. Mark Helm
Speaker
Dr. Marion Stemke
Executive officer and Coordinator
Claudia Alihodzic
Administrator TRR319
Members of the Scientific Board
Recent publications from the TRR 319
Wierczeiko A, Pastore S, Mündnich S, Busch AM, Dietrich V, Helm M, Butto T, Gerber S. NanopoReaTA: a user-friendly tool for nanopore-seq real-time transcriptional analysis. Bioinformatics. 2023 Aug 7:btad492. doi: 10.1093/bioinformatics/btad492. Epub ahead of print. PMID: 37549052.
García-Vílchez R, Añazco-Guenkova AM, Dietmann S, López J, Morón-Calvente V, D’Ambrosi S, Nombela P, Zamacola K, Mendizabal I, García-Longarte S, Zabala-Letona A, Astobiza I, Fernández S, Paniagua A, Miguel-López B, Marchand V, Alonso-López D, Merkel A, García-Tuñón I, Ugalde-Olano A, Loizaga-Iriarte A, Lacasa-Viscasillas I, Unda M, Azkargorta M, Elortza F, Bárcena L, Gonzalez-Lopez M, Aransay AM, Di Domenico T, Sánchez-Martín MA, De Las Rivas J, Guil S, Motorin Y, Helm M, Pandolfi PP, Carracedo A, Blanco S. METTL1 promotes tumorigenesis through tRNA-derived fragment biogenesis in prostate cancer. Mol Cancer. 2023 Jul 29;22(1):119. doi: 10.1186/s12943-023-01809-8. PMID: 37516825; PMCID: PMC10386714.
Koch J, Neuberger M, Schmidt-Dengler M, Xu J, Carneiro VC, Ellinger J, Kriegmair MC, Nuhn P, Erben P, Michel MS, Helm M, Rodríguez-Paredes M, Nientiedt M, Lyko F. Reinvestigating the clinical relevance of the m6A writer METTL3 in urothelial carcinoma of the bladder. iScience. 2023 Jul 11;26(8):107300. doi: 10.1016/j.isci.2023.107300. PMID: 37554463; PMCID: PMC10405067.
Iyer KV, Müller M, Tittel LS, Winz ML. Molecular Highway Patrol for Ribosome Collisions. Chembiochem. 2023 Jun 29:e202300264. doi: 10.1002/cbic.202300264. Epub ahead of print. PMID: 37382189.
Yan L, Yin Z, Zhang H, Zhao Z, Wang M, Müller A, Kallenborn F, Wichmann A, Wei Y, Niu B, Schmidt B, Liu W. RabbitQCPlus 2.0: More Efficient and Versatile Quality Control for Sequencing Data. Methods. 2023 Jun 15:S1046-2023(23)00099-3. doi: 10.1016/j.ymeth.2023.06.007. PMID: 37330158.
Fradera-Sola A, Nischwitz E, Bayer ME, Luck K, Butter F. RNA-dependent interactome allows network-based assignment of RNA-binding protein function. Nucleic Acids Res. 2023 Jun 9;51(10):5162-5176. doi: 10.1093/nar/gkad245. PMID: 37070168; PMCID: PMC10250244.
Zhang H, Song H, Xu X, Chang Q, Wang M, Wei Y, Yin Z, Schmidt B, Liu W. RabbitFX: Efficient Framework for FASTA/Q File Parsing on Modern Multi-Core Platforms. IEEE/ACM Trans Comput Biol Bioinform. 2023 Jun 5;20(3):2341-2348. doi: 10.1109/TCBB.2022.3219114. Epub 2023 Jun 5. PMID: 36327193.
Rücklé C, Körtel N, Basilicata MF, Busch A, Zhou Y, Hoch-Kraft P, Tretow K, Kielisch F, Bertin M, Pradhan M, Musheev M, Schweiger S, Niehrs C, Rausch O, Zarnack K, Keller Valsecchi CI, König J. RNA stability controlled by m6A methylation contributes to X-to-autosome dosage compensation in mammals. Nat Struct Mol Biol. 2023 May 18. doi: 10.1038/s41594-023-00997-7. PMID: 37202476.
For a constantly updated PubMed-library of TRR319 publications, please click here.
