RNA modification and Processing

Welcome to Transregio 319 RMaP

What is RMaP?

Transregio 319 RMaP is a joint venture combining:

Molecular Biology, Biochemistry, Cellular Biology, Chemical Biology, Biophysical Chemistry, Structural Biology, Developmental Biology, Genetics, Bioinformatics.

Principal Investigators of RMaP

Falk Butter

JGU
A03, C03

Prof. Dr. Alexander Dalpke

TU-Dresden
A03

Prof. Dr. Christoph Dieterich

Uni-HD
B01, C02

Prof. Dr. Michaela Frye

UDKFZ
A01

Prof. Dr. Mark Helm

JGU
A05, C01, C03

Prof. Dr. Andreas Hildebrandt

JGU
C01, C02

Prof. Dr. Andres Jäschke

Uni-HD
A02, C03

Prof. Dr. René Ketting

JGU
B04

Dr. Julian König

JGU
B01

Prof. Dr. Frank Lyko

DKFZ
A01

Prof. Dr. F. Nina Papasvasiliou

DKFZ
A04

Dr. Jirka Peschek

Uni-HD
A06

Prof. Dr. Jean-Yves Roignant

JGU
B01

Dr. Alessia Ruggieri

Uni-HD
A05, IRTG

Prof. Dr. Tanja Schirmeister

JGU
A01

Bertil Schmidt, Prof. Dr.

JGU
C01

Prof. Dr. Irmgard Sinning

Uni-HD
B03

Prof. Dr. Dr. Georg Stöcklin

Uni-HD
A04

Dr. Francesca Tuorto

Uni-HD
A06

Dr. Marie-Luise Winz

JGU
B05

Structure of RMaP

A „Modificationslook for Processing“

B „Processing looks for Modifications“

C „New RNA Technology for RMaP“

TRR Speaker Office

Prof. Dr. Mark Helm

Speaker

Dr. Marion Stemke

Executive officer and Coordinator

Claudia Alihodzic

Administrator TRR319

Recent publications from the TRR 319

Zimmermann RA, Fischer TR, Schwickert M, Nidoieva Z, Schirmeister T, Kersten C. Chemical Space Virtual Screening against Hard-to-Drug RNA Methyltransferases DNMT2 and NSUN6. Int J Mol Sci. 2023 Mar 24;24(7):6109. doi: 10.3390/ijms24076109. PMID: 37047081 ; PMCID: PMC10094593.

Bessler L, Vogt LM, Lander M, Dal Magro C, Keller P, Kühlborn J, Kampf CJ, Opatz T, Helm M. A New Bacterial Adenosine-Derived Nucleoside as an Example of RNA Modification Damage. Angew Chem Int Ed Engl. 2023 Mar 6;62(11):e202217128. doi: 10.1002/anie.202217128. Epub 2023 Feb 7. PMID: 36629490.

Koshla O, Vogt LM, Rydkin O, Sehin Y, Ostash I, Helm M, Ostash B. Landscape of Post-Transcriptional tRNA Modifications in Streptomyces albidoflavus J1074 as Portrayed by Mass Spectrometry and Genomic Data Mining. J Bacteriol. 2023 Jan 26;205(1):e0029422. doi: 10.1128/jb.00294-22. Epub 2022 Dec 5. PMID: 36468867 ; PMCID: PMC9879100.

Lemsara A, Dieterich C, Naarmann-de Vries IS. Mapping of RNA Modifications by Direct Nanopore Sequencing and JACUSA2. Methods Mol Biol. 2023;2624:241-260. doi: 10.1007/978-1-0716-2962-8_16. PMID: 36723820.

For a constantly updated list of TRR319 publications, please click here.

Upcoming Events

RNA Biochemistry Meeting October 2023

Read more

RMaP Retreat 13th July 2023 @IMB Mainz

Read more

IMB Postdoc Symposium

Read more

Talk ‘Es war einmal die RNA’ by Julian König, May 24th 2023

Read more

Equal Opportunities 03.05.2023 RMU Weeks

Read more