RNA modification and Processing
Welcome to Transregio 319 RMaP
What is RMaP?
Transregio 319 RMaP is a joint venture combining:
Molecular Biology, Biochemistry, Cellular Biology, Chemical Biology, Biophysical Chemistry, Structural Biology, Developmental Biology, Genetics, Bioinformatics.
Structure of RMaP
A „Modificationslook for Processing“
B „Processing looks for Modifications“

C „New RNA Technology for RMaP“
TRR Speaker Office

Prof. Dr. Mark Helm
Speaker

Dr. Marion Stemke
Executive officer and Coordinator

Claudia Alihodzic
Administrator TRR319
Recent publications from the TRR 319
Zimmermann RA, Fischer TR, Schwickert M, Nidoieva Z, Schirmeister T, Kersten C. Chemical Space Virtual Screening against Hard-to-Drug RNA Methyltransferases DNMT2 and NSUN6. Int J Mol Sci. 2023 Mar 24;24(7):6109. doi: 10.3390/ijms24076109. PMID: 37047081 ; PMCID: PMC10094593.
Bessler L, Vogt LM, Lander M, Dal Magro C, Keller P, Kühlborn J, Kampf CJ, Opatz T, Helm M. A New Bacterial Adenosine-Derived Nucleoside as an Example of RNA Modification Damage. Angew Chem Int Ed Engl. 2023 Mar 6;62(11):e202217128. doi: 10.1002/anie.202217128. Epub 2023 Feb 7. PMID: 36629490.
Koshla O, Vogt LM, Rydkin O, Sehin Y, Ostash I, Helm M, Ostash B. Landscape of Post-Transcriptional tRNA Modifications in Streptomyces albidoflavus J1074 as Portrayed by Mass Spectrometry and Genomic Data Mining. J Bacteriol. 2023 Jan 26;205(1):e0029422. doi: 10.1128/jb.00294-22. Epub 2022 Dec 5. PMID: 36468867 ; PMCID: PMC9879100.
Lemsara A, Dieterich C, Naarmann-de Vries IS. Mapping of RNA Modifications by Direct Nanopore Sequencing and JACUSA2. Methods Mol Biol. 2023;2624:241-260. doi: 10.1007/978-1-0716-2962-8_16. PMID: 36723820.
For a constantly updated list of TRR319 publications, please click here.